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Carprofen is a non steroidal anti-inflammatory that is used by veterinarians for the relief of arthritic systems in dogs. It can be used for joint pain or post operative inflammation. Carprofen, is al so used for the relief from pain and inflammation associated with osteoarthritis, hip dysplasia and other joint issues.
Carprofen is used for pain relief in rheumatoid arthritis, osteoarthritis, acute gout, extra-articular rheumatism, etc.
Items | Specifications | Results |
Appearance | White or almost white crystalline powder | Conforms |
Solubility | Practically insoluble in water ,freely soluble in acetone ,soluble in methanol ,slightly soluble in 2-propanol. | Conforms |
Identification | Infrared absorption spectrum corresponds to that of the reference standard | Conforms |
Appearance of solution | The solution is clear and not more than intensely coloured than reference solution BY3 | Conforms |
Loss on drying | ≤0.5% | 0.22% |
Sulphated ash | ≤0.1% | 0.07% |
Heavy metals | ≤0.002% | Conforms |
Related substances | Unspecified impurities ≤0.2% | 0.09% |
Total impurities ≤0.5% | 0.26% | |
Assay (on dried basis) | 98.5% - 101.5% | 99.1% |
Residual solvent | Acetone ≤5000ppm | Not detected |
Organic volatile impurity | Methylene chloride ≤500ppm | Not detected |
Conclusion | The product conforms to the Enterprise Standard. |
Product parameters | |
Cas number: | 53716-49-7 |
Appearance: | White crystalline powder |
Purity: | 99%min |
Package details: | 20kg/drum |
Brand: | Fortunachem |
Carprofen is a non-steroidal anti-inflammatory drug (NSAID) used primarily in veterinary medicine, most commonly for dogs. It is a prescription medication marketed under various brand names, with Rimadyl being the most well-known.
Its primary function is to reduce pain and inflammation. Think of it as being similar to ibuprofen or naproxen for humans, but it is specifically formulated for dogs and is much safer for them than human NSAIDs.
Carprofen works by inhibiting enzymes called cyclooxygenases (COX enzymes). These enzymes are responsible for producing prostaglandins, which are chemicals in the body that promote inflammation, fever, and pain.
By blocking these enzymes, Carprofen effectively:
Reduces inflammation
Alleviates pain
Lowers fever
It is considered a "COX-2 selective" inhibitor, meaning it primarily targets the COX-2 enzyme associated with inflammation, while largely sparing the COX-1 enzyme that helps maintain normal functions in the stomach lining and kidneys. This selectivity is what helps make it safer for dogs than non-selective NSAIDs.
Carprofen is prescribed by veterinarians to manage pain and inflammation associated with:
Osteoarthritis: It is widely used for long-term management of chronic joint pain and inflammation in dogs.
Post-Surgical Pain: It is frequently given after surgeries (like spays, neuters, or orthopedic procedures) to control pain and help with recovery.
Other Inflammatory Conditions: It can be used for soft tissue injuries or other painful conditions as determined by a veterinarian.
While Carprofen is safe and effective for most dogs when used as prescribed, it is a powerful medication that requires careful veterinary supervision.
Administration: It is available in tablets (chewable and non-chewable), caplets, and an injectable form. The injectable form is typically used in a clinical setting.
Common Side Effects: These are usually mild but can include:
Vomiting
Diarrhea
Decreased appetite
Lethargy
Serious Side Effects (require immediate veterinary attention):
Gastrointestinal Ulcers: Signs include black, tarry stools, vomiting blood, or abdominal pain.
Liver or Kidney Toxicity: Increased drinking/urination, yellowing of gums/skin (jaundice).
Rare Skin Reactions
Contraindications: It should not be used in:
Dogs with known hypersensitivity to Carprofen or other NSAIDs.
Dogs with pre-existing kidney, liver, or gastrointestinal bleeding issues.
It should NEVER be given to cats, as it is highly toxic to them.
Drug Interactions: It should not be used with other NSAIDs (e.g., aspirin, meloxicam, deracoxib) or corticosteroids (e.g., prednisone), as this significantly increases the risk of severe side effects like stomach ulcers.
Aspect | Description |
---|---|
What it is | A veterinary-specific NSAID (non-steroidal anti-inflammatory drug). |
Common Brand Name | Rimadyl (among others). |
Primary Use | To manage pain and inflammation from osteoarthritis and surgery in dogs. |
Key Benefit | Effective pain relief that significantly improves mobility and quality of life. |
Critical Warning | Requires a veterinarian's prescription and monitoring. Never give human NSAIDs to pets. |
Disclaimer: This information is for educational purposes only. Carprofen is a prescription medication that must be used under the direct guidance and supervision of a licensed veterinarian. Always follow your vet's dosage instructions and monitor your pet for any adverse reactions.
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