Name: China Factory Supplier High Quality Good Service Rebamipide CAS 90098-04-7
Brand: Wuhan Fortuna Chemical Co., Ltd.

Specifications of Rebamipide CAS 90098-04-7

Items	Specification	Result
Assay	≥99.0%	99.6%
Apperance	White or almost white crystaline powder	Conforms
Related substances	≤0.4%	0.13%
Loss on drying	≤3.0%	1.8%
Heavy metals	≤10ppm	Conforms
Residue on ignition	≤0.07%	0.05%

Parameters of Rebamipide CAS 90098-04-7

Product parameters
Cas number:	90098-04-7
Appearance:	White or almost white crystaline powder
Purity:	99%min
Package details:	1kg/foil bag;25kg/drum
Brand:	Fortunachem

Rebamipide is a medication primarily used for the treatment and prevention of gastric ulcers and gastritis (inflammation of the stomach lining). It is classified as a mucoprotective agent, meaning it works by protecting the inner lining (mucosa) of the stomach and intestines, rather than by reducing acid production like more common drugs such as proton-pump inhibitors (e.g., omeprazole).

It is widely prescribed in several Asian countries, including Japan and South Korea, and is also available in other parts of the world.

How Does It Work? (Mechanism of Action)

Rebamipide has a unique multi-faceted approach to healing the gastrointestinal tract:

Stimulates Mucus Production: It enhances the synthesis and secretion of prostaglandins (key substances that protect the stomach lining) and increases the production of gastric mucus. This mucus forms a protective barrier against stomach acid, digestive enzymes, and other irritants.

Promotes Healing: It stimulates the proliferation of cells in the stomach lining, accelerating the repair of damaged tissue and the healing of ulcers.

Anti-Inflammatory Effects: It scavenges for and reduces oxygen-free radicals, which are harmful molecules that contribute to inflammation and tissue damage in the gut.

Maintains Blood Flow: It helps maintain healthy blood flow to the gastric mucosa, which is essential for delivering nutrients and oxygen for repair.

In short, while acid-suppressors create a less hostile environment, Rebamipide actively fortifies and repairs the stomach's natural defenses.

Primary Uses and Applications

Gastric and Duodenal Ulcers: Used to treat existing ulcers and prevent their recurrence.
Acute and Chronic Gastritis: Used to relieve symptoms and heal inflammation of the stomach lining, often caused by factors like stress, alcohol, or NSAIDs (e.g., ibuprofen, aspirin).
Prevention of NSAID-Induced Damage: Prescribed to counteract the harmful effects of long-term nonsteroidal anti-inflammatory drug (NSAID) use on the stomach.
Other Conditions: It is sometimes investigated for use in other mucosal conditions, such as dry mouth (xerostomia) and certain eye disorders (like dry eye disease), due to its ability to promote mucus production and healing on other surfaces.

Administration and Dosage

Rebamipide is typically administered orally as a tablet (e.g., 100 mg strength). The standard adult dosage is usually one tablet taken three times daily (after meals).

Key Considerations

Side Effects: Generally well-tolerated. The most common side effects are mild and may include gastrointestinal symptoms like constipation, diarrhea, or nausea. Skin rash and elevated liver enzymes have also been reported in some cases.
Pregnancy and Lactation: The safety of Rebamipide during pregnancy and breastfeeding has not been fully established. It should be used only if clearly needed and under medical supervision.
Not an Acid Reducer: It is important to note that Rebamipide is not an antacid. It does not provide immediate relief from heartburn. Its action is slower and focuses on long-term healing and protection.
Availability: It is a prescription drug and not available over-the-counter.

Summary

Aspect	Description
Drug Class	Mucoprotective agent, gastroprotective drug.
Primary Use	Treatment and prevention of gastric ulcers and gastritis.
Mechanism	Protects and heals the stomach lining by boosting mucus, promoting cell growth, and reducing inflammation.
Key Feature	Works by strengthening the stomach's defense system rather than suppressing acid.
Common Form	Oral tablets (typically 100 mg).

In essence, Rebamipide is a unique drug that focuses on healing and fortifying the stomach's natural protective barrier, making it a valuable tool, especially in managing damage caused by inflammation and long-term use of medications like NSAIDs.