Glibenclamide is mainly used to treat mild and moderate non-insulin-dependent diabetes mellitus. Glibenclamide can selectively act on pancreatic β cells, promote insulin secretion, enhance the hypoglycemic effect of exogenous insulin, and strengthen the receptor effect of insulin. Glibenclamide is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production.
|Apperance||White crystalline powder||White crystalline powder|
|Loss on drying||≤0.5%||0.3%|
|Residue on ignition||≤0.1%||<0.1%|
|Appearance:||White crystalline powder|
|Package details:||1kg/foil bag;25kg/drum|
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