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D-(+)-Mannose is used as a sweetener.
D-(+)-Mannose is a carbohydrate that is important in the glycosylation of molecules in a variety of cellular processes. It is involved in N and O glycosylation of bovine why protein products, used in inf ant formulas. It is also responsible for the O-glycosylation of the T helper cell-derived cytokine interlukin-17A, an important cell-signaling molecule.
| Items | Specifications | Results |
| Appearance | White crystalline powder | Conforms |
| Assay | ≥99.0% | 99.23% |
| Product parameters | |
| Cas number: | 3458-28-4 |
| Appearance: | White crystalline powder |
| Purity: | 99%min |
| Package details: | 25kg/drum |
| Brand: | Fortunachem |
### **Applications of D-Mannose**
D-Mannose is a natural sugar with **targeted health benefits**, primarily for urinary tract health, but also for gut immunity and metabolic support. Below are its key applications:
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### **1. Urinary Tract Health (Primary Use)**
#### **① Prevention & Treatment of UTIs**
- **Mechanism**: Binds to **E. coli** (the bacteria causing ~90% of UTIs), preventing them from adhering to bladder walls.
- **Clinical Support**: Studies show it reduces UTI recurrence by up to **50%** (similar to low-dose antibiotics but without resistance risks).
- **Dosage**:
- **Prevention**: 2 g/day.
- **Acute UTI**: 1.5 g, 2–3x/day (with antibiotics if needed).
#### **② Alternative to Antibiotics**
- Used for **chronic UTIs** in antibiotic-resistant cases.
- Often combined with **cranberry extract** or **probiotics** (e.g., *Lactobacillus*) for enhanced effects.
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### **2. Gut & Immune Support**
- **Prebiotic Effect**: Feeds beneficial gut bacteria (e.g., *Bifidobacteria*).
- **Glycoprotein Synthesis**: Supports immune cell communication.
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### **3. Rare Metabolic Disorders**
- Treats **CDG (Congenital Disorders of Glycosylation)**, a genetic condition affecting sugar-protein binding.
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### **4. Veterinary Use**
- Prevents **UTIs in dogs and cats** (vet-prescribed formulations).
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### **Safety & Considerations**
- **Side Effects**: Rare (mild bloating or diarrhea at high doses).
- **Diabetics**: Safe in moderation (minimal blood sugar impact).
- **Pregnancy**: Consult a doctor (limited studies).
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### **Forms & Products**
- **Powders** (e.g., NOW Foods, Pure Encapsulations).
- **Capsules** (combined with probiotics like *Lactobacillus rhamnosus*).
- **Veterinary Formulas** (e.g., VetriScience).
D-Mannose is a **natural, evidence-backed option** for UTI management, with emerging roles in gut health. Always choose **pharmaceutical-grade** products for efficacy.
Used as a sweetener.
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