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Trabectedin is used in the treatment of inoperable or specific advanced soft tissue sarcomas. Trabectedin is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to small grooves in DNA, blocks transcription of stress-induced proteins, induces DNA backbone lysis and apoptosis, and increases ROS production in MCF-7 and MDA-MB-453 cells.
| Items | Specifications | Results |
| Appearance | White or off-white powder | Conforms |
| Assay | ≥98.0% | 99.15% |
| Product parameters | |
| Cas number: | 114899-77-3 |
| Appearance: | White or off-white powder |
| Purity: | 98%min |
| Package details: | 1g/vial; 10g/PE bottle |
| Brand: | Fortunachem |

A tetrahydroisoquinoline alkaloid with antitumor activity isolated from the Caribbean tunicate, Ecteinascidin turbinata.

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