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Neohesperidin is a natural new nutritional sweetener extracted from citrus fruits, which is widely used in fruit juices, fruit wines, beverages, pastries and pharmaceutical formulations, especially suitable as a food for diabetic patients.
Neohesperidin is a flavonoid found in citrus fruit peel that has diverse biological activities. In vitro, it inhibits osteoclast differentiation, bone resorption, calcium oscillations, and activation of NF-κB and nuclear factor of activated T cells (NFAT) by receptor activator of NF-κB ligand (RANKL). In vivo, neohesperidin administration protects ovariectomized mice from bone loss. Neohesperidin acts as a hypolipidemic agent, reducing lipid accumulation in HepG2 cells and reversing hyperlipidemia in a mouse model of diet-induced obesity. In a mouse model of diabetes, neohesperidin increases glucose tolerance and decreases insulin resistance while simultaneously decreasing serum triglycerides and total cholesterol and inhibiting lipid accumulation in livers in vivo.
Items | Specification |
| Appearance | Light yellow crystals or crystalline powder |
| Assay | ≥95% |
| Molecular Formular | C28H34O15 |
| Molecular Weight | 610.56 |
| EINECS | 236-216-9 |
| Product parameters | |
| Cas number: | 13241-33-3 |
| Appearance: | Light yellow crystals or crystalline powder |
| Purity: | 95%min |
| Package details: | 1kg/foil bag;25kg/drum or per your request |
| Brand: | Fortunachem |
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