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Linaclotide can be used to treat constipated irritable bowel syndrome and chronic idiopathic constipation.
Linaclotide is a guanylate cyclase C agonist that, when bound to intestinal GC-C, results in elevated intracellular and extracellular cyclic guanylate (cGMP) concentrations. Elevated intracellular cGMP can stimulate the intestinal fluid secretion and accelerate gastrointestinal migration, thereby increasing bowel frequency; Elevated extracellular cGMP concentrations reduce pain sensitivity and bowel pain.
| item | specification | result |
| Appearance | white powder | conform |
| purity | 99%min | 99.6% |
| Product parameters | |
| Cas number: | 851199-59-2 |
| Appearance: | white powder |
| Purity: | 99.0%min |
| Package details: | 25Kg/Drum |
| Brand: | Fortunachem |

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