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L-Tryptophan is used as a nutritional enhancers.
L-tryptophan is one of the essential amino acids in human and animal life activities, which plays an important role in the growth and development and metabolism of humans and animals, and is known as the second essential amino acid. In medicine, L-tryptophan can synthesize hormones such as hydroxytryptamine and physiologically active substances such as pigments, alkaloids, coenzymes, and plant hormones in the human body, which can prevent and treat pellagnoderma. As an aromatic amino acid, L-tryptophan has the characteristics of deriving other biologically active substances, as a precursor of neurotransmitters and hormones, involved in the regulation of neurophysiological activities in animals, L-tryptophan's derivative serotonin is a central neurotransmitter, which plays an important role in regulating animal behavior (feeding, fatigue, anxiety).
| Item | Specifications | Results |
| Appearance | White crystals or crystalline powder | Conforms |
| Assay | 98.5% ~101.5% | 99.4% |
| Loss on drying | 0.3% | 0.11% |
| Residue on ignition | 0.10% | 0.05% |
| Product parameters | |
| Cas number: | 73-22-3 |
| Appearance: | White crystals or crystalline powder |
| Purity: | 98.5%~101.5% |
| Package details: | 25kg/drum |
| Brand: | Fortunachem |
L-Tryptophan is an essential amino acid — meaning the human body cannot synthesize it on its own and must obtain it through diet or supplementation. It serves as a precursor to several important biochemical compounds in the body, most notably serotonin and melatonin, which play key roles in mood regulation, sleep, and cognitive function.
Key Roles and Uses of L-Tryptophan
Serotonin Production
L-Tryptophan is converted into 5-hydroxytryptophan (5-HTP), which is then used to produce serotonin, a neurotransmitter that helps regulate:
Mood
Appetite
Anxiety
Depression
Melatonin Synthesis
Serotonin is further converted into melatonin, a hormone critical for regulating the sleep-wake cycle (circadian rhythm).
This makes L-tryptophan potentially useful for improving sleep quality and managing insomnia.
Mood and Mental Health Support
Due to its role in serotonin production, L-tryptophan has been studied for its potential to help with:
Mild to moderate depression
Seasonal affective disorder (SAD)
Premenstrual dysphoric disorder (PMDD)
Appetite Regulation
Serotonin influences satiety signals, so L-tryptophan may help reduce carbohydrate cravings and support healthy eating behaviors.
Cognitive Function
Adequate serotonin levels are linked to better focus, memory, and emotional resilience.
Dietary Sources
L-Tryptophan is found in many protein-rich foods, including:
Turkey and chicken
Eggs
Cheese (especially cottage cheese)
Nuts and seeds (e.g., pumpkin seeds, almonds)
Soy products (tofu, soy milk)
Fish (salmon, tuna)
Oats and bananas (in smaller amounts)
Supplementation Considerations
Typical supplemental doses range from 500 mg to 1,000 mg per day, often taken before bed to support sleep.
Caution: L-Tryptophan should not be combined with antidepressants (especially SSRIs, MAOIs, or SNRIs) without medical supervision due to the risk of serotonin syndrome — a potentially dangerous condition caused by excessive serotonin.
In the late 1980s, a contaminated batch of L-tryptophan supplements was linked to a rare condition called eosinophilia-myalgia syndrome (EMS), leading to temporary bans. Modern, high-quality supplements from reputable sources are considered safe.
Summary
L-Tryptophan is a vital amino acid with significant roles in brain health, mood balance, and sleep regulation. While it’s available in food, targeted supplementation may offer benefits for sleep disorders, mild depression, or stress-related symptoms—when used responsibly and under guidance.
Let me know if you’d like dosage guidelines, comparisons with 5-HTP, or information on clinical studies!



In the food industry, it is mainly used as a nutritional supplement; In the pharmaceutical industry, it is used as a sedative.

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