Name: China Manufacturer Supply High Quality Tirzepatide CAS 2023788-19-2 with good service
Brand: Wuhan Fortuna Chemical Co., Ltd.

Items	Specifications	Results
Appearance	White or off-white powder;Freely soluble in water.	Conforms
Specific Rotation	Calculates on the anhydrous and sodium-ion-free basis,the specific rotation should be -23.5°to -33.5°	-29.7°
Identification	1)The retention time of the main peak of the test solution shall correspond to that of the main peak of the reference solution.	Conforms
	2)Amino Acid Ratio:Asp1.6~2.4、Glu3.2~4.8、Thr 1.6~2.4、Ala3.2~4.8、(Aib)1.6~2.4、Tyr1.6~2.4、Val 0.8~1.2	Conforms
	3)MS:Relative Molecular Mass4813.5±1.0Da	Conforms
pH	6.0~9.0	6.8
Clarity and Color of Solution	The solution shall be clear and colorless.	Conforms
Water Content	≤7.0%	1.3%
Acetic Acid	≤0.5%	0.04%
Trifluoroacetic Acid	≤0.5%	0.01%
Sodium Ion	≤5.0%	1.2%
Residual Solvents	Methanol≤0.3% Dichloromethane≤0.06% Acetonitrile≤0.041% N,N-DMF≤0.088%	0.002% ND 0.008% ND
High Molecular Weight Substances	Single impurity≤0.3% Total impurities≤0.8%	0.04% 0.04%
Related Substances	Impurity 1≤0.5% Impurity 2≤0.5% Impurity 3≤0.5% Impurity 4≤0.5% Impurity 5≤0.5% Impurity 6≤0.5% Other single impurity≤0.5% Total impurities≤2.0%	ND ND 0.10% 0.26% 0.10% 0.09% ≤0.24% 0.79%
Purity	≥98.0%	99.2%
Bacterial Endotoxin	The endotoxin in each 1mg of Tirzepatide shall be less than 5EU.	Conforms
Microbial limits	Total Yeasts and Molds Count(TYMC)≤100cfu/g	6.0cfu/g
Microbial limits	Total Yeasts and Molds Count(TYMC)≤100cfu/g	＜1cfu/g
Assay	It contains 95.0% to 105.0% of Tirzepatide,calculated on the anhydrous and sodium-ion-free basis.	100.4%
Assay of Peptide	≥80.0%	96.7%
Conclusion	The product conforms to the above specifications.

Tirzepatide is a synthetic linear peptide comprised of 39 amino acids, chemically modified with a C20 fatty diacid side chain to prolong its action. It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist.

Pharmaceutical vs. Chemical Grade

Pharmaceutical Grade: Marketed as Mounjaro® (for type 2 diabetes) and Zepbound® (for weight management). Formulated for injection.
Chemical/Research Grade: A high-purity (>95%, often >98%), lyophilized (freeze-dried) powder, typically sold in milligram quantities. It is not sterile or formulated for human use.

Primary Uses in Chemical and Research Grades

In this context, it serves as a precise biochemical tool:

Pharmacology & Biochemistry Research:

Mechanism of Action Studies: Used in vitro (cell cultures) and in vivo (animal models) to dissect the signaling pathways, receptor binding kinetics, and downstream effects of dual GIP/GLP-1 agonism.
Comparative Studies: To benchmark efficacy and selectivity against other incretin mimetics (e.g., semaglutide) in controlled experimental systems.

Analytical Reference Standard:

Quality Control: Serves as the primary reference standard in HPLC, LC-MS/MS, and other assays to identify, quantify, and determine the purity of tirzepatide in pharmaceutical development.
Bioanalysis: Used to develop and validate methods for measuring tirzepatide concentrations in biological matrices (plasma, tissues) during preclinical pharmacokinetic studies.

Preclinical Drug Development:

Proof-of-Concept Studies: Employed in animal models of obesity, diabetes, and metabolic syndrome to investigate therapeutic potential, optimal dosing, and safety profiles before clinical trials.
Metabolic Research: A key tool for studying integrated metabolism, energy homeostasis, and appetite regulation in specialized research settings.

Key Distinction for Handling

Not for Human Use: For laboratory research only.
Handling: Requires reconstitution with appropriate buffers. It is a peptide, requiring storage at -20°C or below to maintain stability.
Regulatory: While a research chemical, it is often subject to controlled purchase due to its status as a patented pharmaceutical agent.

Summary

Aspect	Description
Identity	Synthetic 39-amino acid peptide, dual GIP/GLP-1 receptor agonist.
Chemical Grade	High-purity, lyophilized powder for non-therapeutic research.
Primary Research Uses	1. Mechanistic Tool: For studying dual incretin receptor pharmacology. 2. Analytical Standard: For quantification and method validation. 3. Preclinical Agent: For metabolic disease modeling in animals.

In essence, chemical-grade tirzepatide is a critical reference molecule and investigational tool for scientists studying metabolic diseases, developing analytical methods, and advancing understanding of incretin biology.