Name: China Original manufacturer Supply High Quality Beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate CAS 6974-32-9
Brand: Wuhan Fortuna Chemical Co., Ltd.

Specifications of Beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate CAS 6974-32-9

Items	Specifications	Results
Appearance	White or almost white crystalline powder	White crystalline powder
Heavy metals	≤20ppm	Complies
Loss on drying	≤0.5%	0.1%
Residue on ignition	≤0.2%	0.06%
Assay(HPLC)	≥98.0%	99.1%

Parameters of Beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate CAS 6974-32-9

Product parameters
Cas number:	6974-32-9
Appearance:	White crystalline powder
Purity:	98%min
Package details:	1kg/foil bag
Brand:	Fortunachem

beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate is a chemically synthesized, fully protected derivative of the simple sugar D-ribose. Its structure and properties are defined by its core sugar ring and the specific protecting groups attached to it.

1. Core Structure: beta-D-Ribofuranose

D-Ribose: This is a five-carbon sugar (a pentose), most famous as the sugar backbone of RNA (Ribonucleic Acid).
Furanose: This term indicates that the sugar has formed a five-membered ring (consisting of four carbon atoms and one oxygen atom), which is characteristic of ribose in biological systems, as opposed to a six-membered "pyranose" ring.
beta- This denotes the configuration of the anomeric carbon (carbon-1). In the beta-configuration, the substituent at the anomeric carbon is on the same side of the ring plane as the -CH₂OH group (on carbon-5 in the standard Haworth projection).

2. Protecting Groups: Acetate and Benzoates
This molecule is not found in nature; it is deliberately created in a laboratory for organic synthesis. The purpose of the attached groups is to block specific reactive sites (the hydroxyl groups) to allow for selective chemical reactions elsewhere.

1-acetate: The hydroxyl group on the anomeric carbon (carbon-1) is protected as an acetate ester. This group is relatively more labile (easier to remove) than the benzoate groups under specific conditions (e.g., with ammonia or a mild base).
2,3,5-tribenzoate: The hydroxyl groups on carbons 2, 3, and 5 are all protected as more stable benzoate esters.

Primary Application and Significance

The main utility of this compound is as a crucial chemical building block (synthon) in the synthesis of nucleosides and nucleotides. These are the fundamental monomers that make up RNA and DNA, as well as many important drugs (e.g., antiviral and anticancer agents like Ribavirin).

Its strategic value lies in the differential reactivity of its protecting groups:

The anomeric acetate can be selectively removed under mild conditions that leave the benzoate groups intact.
Once the anomeric position is deprotected, it becomes a reactive site that can be coupled with a nucleobase (like adenine, guanine, cytosine, or uracil) to form a ribonucleoside.
After the glycosidic bond is formed, the robust benzoate groups on the ribose ring can be removed in a final deprotection step using stronger basic conditions (e.g., sodium methoxide) to reveal the free hydroxyl groups needed for further chemistry or for the final, biologically active nucleoside.

In summary, beta-D-Ribofuranose 1-acetate 2,3,5-tribenzoate is a meticulously designed, protected sugar intermediate that provides synthetic chemists with precise control for constructing the ribose-containing molecules essential to life and medicine.