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The main physiological functions of glutathione are scavenging free radicals, antioxidant, and anti-aging. It is the main free radical scavenger in the body. Glutathione not only scavenges free radicals in the body, but also improves immunity. It not only enhances the function of blood cells in the production of protective substances (protective substances are substances that protect the body from infection), but also reduces the total content of inflammatory substances in the body, which are made by cells.
Glutathione is a tripeptide compound formed by condensation of glutamic acid, cysteine, and glycine by peptide bonds. It has the effects of antioxidant, scavenging free radicals, detoxification, enhancing immunity, delaying aging, anti-cancer, anti-radiation hazards and so on.
Item | Specifications | Results |
Appearance | White or almost white crystalline powder | White crystalline powder |
Heavy Metal | ≤10ppm | Conform |
Loss on drying | ≤0.5% | 0.3% |
Sulfated ash | ≤0.1% | 0.07% |
Assay | 98% - 101% | 98.3% |
Product parameters | |
Cas number: | 70-18-8 |
Appearance: | White or almost white crystalline powder |
Purity: | 98.0% - 101.0% |
Package details: | 1kg/foil bag;25kg/drum |
Brand: | Fortunachem |
Glutathione (often abbreviated as GSH) is a potent antioxidant produced naturally in the body's cells. It is often called the "master antioxidant" because of its critical role in protecting cells from damage and maintaining other antioxidants, like vitamins C and E, in their active forms.
Chemically, it is a tripeptide, meaning it is composed of three amino acids: cysteine, glutamate, and glycine.
Glutathione's importance stems from its multifaceted functions:
1. Powerful Antioxidant Activity:
It neutralizes harmful free radicals and reactive oxygen species (ROS) that are generated through normal metabolism, exposure to toxins, and radiation. This oxidative stress damages cells, proteins, and DNA and is linked to aging, cancer, and numerous diseases.
2. Detoxification:
It is a key component of the liver's detoxification system. Glutathione binds to toxins, heavy metals, drugs, and carcinogens, making them water-soluble so they can be excreted from the body through urine or bile.
3. Immune System Support:
It is essential for the optimal function of lymphocytes (white blood cells), helping the body fight infections and diseases. It also plays a role in regulating inflammation.
4. Cellular Function and DNA Synthesis:
It is involved in vital cellular processes, including protein synthesis, enzyme function, and the repair and synthesis of DNA.
5. Recycling Other Antioxidants:
As the "master antioxidant," it helps regenerate vitamins C and E after they have neutralized free radicals, maximizing the body's overall antioxidant capacity.
Levels of glutathione can be depleted by:
Aging
Chronic stress
Poor nutrition (diets low in the precursor amino acids)
Environmental toxins and pollution
Chronic diseases (e.g., diabetes, cancer, HIV/AIDS)
Certain medications
Excessive alcohol consumption
Since oral glutathione supplements are poorly absorbed by the gut, the most effective strategies focus on providing the building blocks or supporting its production:
Diet:
Sulfur-Rich Foods: Cruciferous vegetables (broccoli, cauliflower, Brussels sprouts, kale), garlic, onions, and shallots.
High-Quality Protein: Provides the amino acid building blocks (especially cysteine).
Other Foods: Avocado, spinach, asparagus, and okra.
Supplements (Precursors):
N-acetylcysteine (NAC): A highly effective precursor that is converted into cysteine in the body.
Alpha-Lipoic Acid (ALA): Helps recycle glutathione.
Milk Thistle (Silymarin): Supports glutathione levels in the liver.
Vitamin C & E: Help maintain glutathione levels.
Selenium: A essential mineral that is a cofactor for the glutathione peroxidase enzyme.
Lifestyle:
Regular, moderate exercise has been shown to boost glutathione levels.
Adequate sleep and stress reduction are also beneficial.
Glutathione is promoted for a wide range of purposes, including:
Anti-aging (by reducing oxidative stress)
Supporting liver health (especially in non-alcoholic fatty liver disease)
Supporting immune function in chronic illnesses
Improving skin health and promoting a brighter complexion (often used in high-dose IV treatments for this purpose)
Supporting mental health and cognitive function
Important Note: While its role in the body is undeniable, evidence for the effectiveness of oral glutathione supplements for many health claims is still evolving. Intravenous (IV) administration is more direct but should only be done under medical supervision.
In summary, glutathione is a fundamental molecule for maintaining cellular health, combating oxidative stress, and detoxifying the body. Supporting its natural production through a healthy diet and lifestyle is the most well-established approach to maintaining optimal levels.
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