Name: China Manufacturer Supply High Quality Cytidine 5'-Diphosphocholine CAS 987-78-0
Brand: Wuhan Fortuna Chemical Co., Ltd.

Specifications of Cytidine 5'-Diphosphocholine CAS 987-78-0

Items	Specifications	Results
Appearance	White crystalline or crystalline powder	White crystalline powder
Identification	The infrared absorption spectrum of sample should be consistent with that of reference substance	Complies
Dentification HPLC	The retention time of the major peak in ample solution should be consistent with that in the reference solution	Complies
pH	2.5-3.5	2.53
Clarity and color of solution	The solution should be clear and colorless	Complies
Ammonium	NMT 0.05%	Complies
Heavy metals	NMT 10ppm	Complies
Free phosphoric acids	NMT 0.1%	Complies
Loss on drying	NMT 5.0%	3.72%
Related Substances
5’-CMP	NMT 1.0%	0.32%
Assay(Calculated on dry)	NLT 98.0%	100.92%
Bulk density	0.4-0.5g/ml	0.46
Total plate count	NMT 1000CFU/g	Complies
Fungi count	NMT 100CFU/g	Complies
E.coli	Absent in 1 g	Complies
Arsenic	NMT 2ppm	Complies
Residual solvent
Methanol	NMT 0.3%	0.15%
Conclusion	The product complies with the enterprise standards.

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Parameters of Cytidine 5'-Diphosphocholine CAS 987-78-0

Product parameters
Cas number:	987-78-0
Appearance:	white crystalline powder
Purity:	99.0%min
Package details:	25kg/Carton box
Brand:	Fortunachem

Cytidine 5'-Diphosphocholine (CDP-Choline) is a naturally occurring compound found in every cell of the body and is an essential intermediate in the biosynthesis of phosphatidylcholine, a critical phospholipid that makes up a major part of cell membranes, particularly in the brain.

In simpler terms, it's a potent nootropic and neuroprotective supplement that provides the raw building blocks your brain needs to create and maintain healthy cell membranes and facilitate communication between brain cells.

The Crucial Role: CDP-Choline and Brain Health

To understand CDP-Choline, it's helpful to know what it delivers to the body. When you ingest CDP-Choline, it is broken down into two key components that are readily absorbed and used by the brain:

Cytidine: This is a nucleotide (a building block of RNA). In the brain, cytidine is converted into uridine, which is essential for the synthesis of new neural tissues and synapses.
Choline: This is a vital nutrient, a precursor to the neurotransmitter acetylcholine (crucial for memory, learning, and muscle control) and a key component of phosphatidylcholine.

The power of CDP-Choline lies in this dual mechanism. It efficiently delivers both of these critical compounds directly to the brain, where they work synergistically.

Key Functions and Mechanisms:

Repairs and Builds Cell Membranes: It is a primary source for synthesizing phosphatidylcholine, which is a fundamental structural component of neuronal membranes. By supporting membrane integrity, it helps neurons maintain proper fluidity, flexibility, and function.
Enhances Neurotransmitter Production: The choline component is used to produce acetylcholine, one of the most important neurotransmitters for memory, focus, and cognitive speed.
Boosts Brain Energy Metabolism: It helps increase the synthesis of neural energy reserves and supports cerebral blood flow, ensuring the brain has the fuel it needs to perform optimally.
Protects Against Damage (Neuroprotection): It helps repair damaged neuronal membranes after injury (like a stroke or concussion) and has been shown to reduce the size of the damaged area. It also acts as an antioxidant within the brain.

Natural Sources and Supplementation

While the body can produce some CDP-Choline endogenously, it is also obtained from the diet, though not in the compound form itself. You get the precursors from:

Choline-rich foods: Eggs (especially the yolk), liver, beef, soybeans, peanuts, and cruciferous vegetables like broccoli.
Cytidine/Uridine sources: These are found in foods containing RNA, such as brewer's yeast, organ meats, and tomatoes.

However, just like with NMN, it is difficult to get a therapeutic dose from diet alone. CDP-Choline is widely available as a dietary supplement (often under the name Citicoline) and is also used as a prescription drug in many countries for treating stroke and brain injury.

Potential Benefits and Clinical Evidence

The research on CDP-Choline is more extensive in humans than for many other nootropics, particularly in the context of neurological injury and age-related decline.

Well-Supported Benefits Include:

Stroke Recovery: It is widely used (especially in Europe and Japan) as a pharmaceutical drug to aid recovery from ischemic strokes. It helps repair brain tissue, reduce neurological damage, and improve cognitive and motor function recovery.
Cognitive Enhancement: Studies show it can improve memory, attention, and executive function in both healthy adults and those with age-related cognitive decline.
Brain Injury: Shown to be beneficial in cases of traumatic brain injury (TBI) and concussion by supporting membrane repair.
Eye Health (Glaucoma): It has been studied for its potential to protect retinal neurons and improve visual function in certain types of glaucoma and other optic nerve diseases.
Neurodegenerative Diseases: Research is ongoing for its potential supportive role in conditions like Alzheimer's and Parkinson's disease, primarily by supporting overall brain cell health and acetylcholine levels.

Safety and Side Effects

CDP-Choline is generally considered very safe and well-tolerated. It has a low side-effect profile. The most common potential side effects are mild and may include:

Headache
Gastrointestinal discomfort (nausea, diarrhea)
Insomnia (if taken too close to bedtime due to its cognitive-stimulating effects)
Low blood pressure in some individuals

As always, it's recommended to consult with a healthcare professional before starting any new supplement regimen.

Summary: CDP-Choline vs. NMN

While both are important biomolecules, they have distinct roles:

Feature	β-Nicotinamide Mononucleotide (NMN)	Cytidine 5'-Diphosphocholine (CDP-Choline)
Primary Role	Cellular Energy & DNA Repair	Brain Structure & Neurotransmission
Key Molecule	Boosts NAD+	Provides Choline & Cytidine
Main Target	All cells (especially mitochondria)	Primarily Brain and Nervous System
Primary Benefit	Anti-aging, energy metabolism, activating sirtuins	Neuroprotection, memory, focus, brain repair

In essence, CDP-Choline is a powerhouse for brain-specific structural repair and cognitive function, whereas NMN is a systemic booster for fundamental cellular energy and repair processes.