Name: China Manufacturer Supply High Quality Beta-Nicotinamide Adenine Dinucleotide Disodium Salt Reduced Form (NADH) CAS 606-68-8
Brand: Wuhan Fortuna Chemical Co., Ltd.

Specifications of Beta-Nicotinamide Adenine Dinucleotide Disodium Salt Reduced Form (NADH) CAS 606-68-8

Items	Specifications	Results
Appearance	White to yellowish powder	Complies
Purity	≥98.0%	98.3%
Assay(Dry Basis)	≥95.0%	96.5%
Sodium content	5.5%-7.5%	5.8%
Water content	≤8%	5.9%
PH(1.0g/100ml(25℃))	7.0-10.0	8.8
Heavy Metals	NMT 10ppm	Conform
Pb(ppm)	NMT 1ppm	Conform
As (ppm)	NMT 1ppm	Conform
Cd(ppm)	NMT 1ppm	Conform
Hg(ppm)	NMT 1ppm	Conform
Total Plate Count	NMT 1000 CFU/g	Conform
Yeast&Mold	NMT 100 CFU/g	Conform
E.coil	Negative	Negative
Salmonella	Negative	Negative
Conclusion	This product complies with the specifications.

Parameters of Beta-Nicotinamide Adenine Dinucleotide Disodium Salt Reduced Form (NADH) CAS 606-68-8

Product parameters
Cas number:	606-68-8
Appearance:	White powder
Purity:	95%; 98%
Package details:	100g/bottle; 1kg/foil bag
Brand:	Fortunachem

β-Nicotinamide Adenine Dinucleotide Disodium Salt is the stable, sodium salt form of NAD⁺ (Nicotinamide Adenine Dinucleotide), one of the most crucial molecules in all living cells. It is commonly abbreviated as NAD⁺ disodium salt or β-NAD⁺ Na₂.

To understand this compound, it's best to break down its name:

β-Nicotinamide Adenine Dinucleotide (β-NAD⁺): This is the full name for the coenzyme NAD⁺. It consists of two nucleotides (adenine and nicotinamide) joined together. The "β" denotes the specific three-dimensional configuration of the chemical bond connecting the nicotinamide moiety to the sugar molecule; this is the biologically active form. NAD⁺ is a coenzyme, meaning it acts as an essential helper for enzymes that catalyze vital reactions.
Disodium Salt: This indicates that the molecule has been stabilized by binding two sodium ions (Na⁺) to its phosphate groups. This salt form is more stable, less hygroscopic (absorbs less moisture), and more soluble in water than the free acid form, making it the preferred standard for laboratory and commercial use.

Key Functions and Biological Importance

The fundamental role of the NAD⁺ molecule is to act as a shuttle for electrons and energy in metabolic processes. It constantly cycles between two forms:

NAD⁺ (Oxidized Form): The form provided by this disodium salt. It acts as an electron acceptor.
NADH (Reduced Form): After accepting two electrons and one proton (a hydride ion, H⁻), NAD⁺ is reduced to NADH. NADH carries this energy to another part of the cell.

Its primary biological roles are:

Energy Metabolism: This is its most famous function. NAD⁺ is a key player in glycolysis and the Krebs (Citric Acid) Cycle, where it accepts electrons during the breakdown of glucose and fats. The resulting NADH then donates these electrons to the electron transport chain to produce the bulk of the cell's ATP (adenosine triphosphate), the primary energy currency.
Cellular Repair and Signaling: NAD⁺ is a required substrate for several important enzymes, including:

Sirtuins (SIRTs): Proteins involved in DNA repair, reducing inflammation, and regulating lifespan.
PARPs (Poly-ADP-ribose-polymerases): Enzymes critical for repairing damaged DNA.
Because these enzymes consume NAD⁺, its availability directly influences cellular health, aging, and stress resistance.

Primary Applications of the Disodium Salt

The β-NAD⁺ disodium salt is not typically used as a direct dietary supplement due to poor absorption. Its main applications are scientific and industrial:

Enzyme Assays: It is an essential reagent in clinical diagnostics and biochemical research to measure the activity of hundreds of dehydrogenase enzymes (e.g., lactate dehydrogenase - LDH, alcohol dehydrogenase - ADH). The reaction rate is tracked by measuring the conversion of NAD⁺ to NADH, which absorbs light at 340 nm.
Cell Culture: It is added to cell culture media to support the metabolic needs of growing cells in the lab.
Cofactor Supplementation: Used in in vitro enzymatic synthesis to drive reactions that require NAD⁺ as a cofactor.
Research: Scientists use it to study cellular metabolism, aging, neurodegeneration, and the mechanisms of the enzymes that depend on it (sirtuins, PARPs).

Summary

In essence, β-Nicotinamide Adenine Dinucleotide Disodium Salt is the stable, commercially available form of the vital coenzyme NAD⁺. It serves as an indispensable tool in biochemistry and medicine to study and facilitate the very reactions that power life, from energy production to DNA repair. Its importance lies in its role as the oxidized, electron-accepting form of the NAD⁺/NADH redox couple.