Name: China Supplier High Quality Best Price D-(-)-Asparagine monohydrate CAS 2058-58-4
Brand: Wuhan Fortuna Chemical Co., Ltd.

D-(-)-Asparagine monohydrate is a specific stereoisomer of the amino acid asparagine, crystallized with one molecule of water. To break down its name:

Asparagine (Asn, N): This is one of the 20 common amino acids that form the building blocks of proteins. It was the first amino acid to be isolated (from asparagus juice, hence its name). It is classified as a neutral, polar amino acid due to the amide group in its side chain.
D-(-): This prefix is crucial. It specifies the molecule's chirality, or "handedness."

Most amino acids found in proteins are the L- stereoisomer. L-Asparagine is the biologically active form used by living organisms in protein synthesis and metabolism.
D-Asparagine is the mirror-image molecule. It is not incorporated into proteins by the standard cellular machinery and is relatively rare in nature. The (-) indicates it is levorotatory, meaning it rotates plane-polarized light to the left.

Monohydrate: This means the crystalline form of this D-Asparagine molecule has one molecule of water (H₂O) associated with it per molecule of asparagine. This water of hydration helps stabilize the crystal structure.

Properties and Characteristics

Chemical Formula: C₄H₈N₂O₃ · H₂O
Appearance: Typically a white, crystalline powder.
Solubility: Generally soluble in water.
Biological Role: Unlike its L-counterpart, D-Asparagine is not a primary building block for proteins. However, it is found in some specific biological contexts:

It is present in certain bacterial cell walls and some antibiotics.
It has been identified in the human brain and other tissues, where it is believed to play a role in neuroendocrine and nervous system function, potentially acting as a neurotransmitter or neuromodulator.

Key Differences from L-Asparagine

Feature	D-(-)-Asparagine	L-Asparagine
Stereochemistry	"Right-handed" mirror image	"Left-handed," the standard form
Biological Role	Non-proteinogenic; specialized roles	Proteinogenic (builds proteins); key in metabolism
Metabolism	Not metabolized by standard pathways	Incorporated into proteins and central to nitrogen metabolism
Prevalence	Rare in nature	Abundant in all life forms

Common Applications and Uses

Biochemical Research: It is primarily used as a research reagent.

To study the specific biological functions and pathways of D-amino acids in the nervous system and endocrine system.
To investigate enzymes that interact with D-amino acids.
Used as a standard in analytical chemistry (e.g., chiral chromatography) to separate and identify different amino acid isomers.

Cell Culture: It may be used in specific microbial culture media.
Food and Feed Additive: While less common, it can be used in specialized applications.

In summary, D-(-)-Asparagine monohydrate is the non-proteinogenic, mirror-image form of the common amino acid asparagine, supplied as a stable crystalline hydrate, and is most importantly used as a tool in scientific research to understand the unique roles of D-amino acids in biology.