API Manufacturers in USA 2022

Pharmaceutical and biotechnology companies gain huge revenues in the North American Active Pharmaceutical Ingredients (API) market, so companies continue to increase their investment in synthetic APIs to increase the possibility of revenue, especially for small molecule drugs. With the rise of more and more pharmaceutical companies in the Asia Pacific region, API companies in North America have also increased their R&D investment. This article will introduce API manufacturers in US in detail.

Table: API Manufacturers in USA

Eli Lilly and Company

Indianapolis, IN

PfizerNew York, NY
ABBVIENorth Chicago, IL
Bristol-Myers SquibbNew York, NY
Ashland Specialty IngredientsWilmington, DE
Parchem - Fine & Specialty ChemicalsNew Rochelle, NY
SAFC PharmaSt. Louis, MO
BoroPharm Inc.Novi, MI

Eli Lilly and Company is an American pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries. Its products are sold in approximately 125 countries. The company was founded in 1876 by, and named after, Colonel Eli Lilly, a pharmaceutical chemist and veteran of the American Civil War.


Pfizer develops and produces medicines and vaccines for immunology, oncology, cardiology, endocrinology, and neurology. The company has several blockbuster drugs or products that each generate more than US$1 billion in annual revenues. In 2020, 52% of the company's revenues came from the United States, 6% came from each of China and Japan, and 36% came from other countries.


AbbVie is an American publicly traded biopharmaceutical company founded in 2013. It originated as a spin-off of Abbott Laboratories.


Bristol-Myers Squibb Company (BMS) is an American multinational pharmaceutical company. Headquartered in New York City, BMS is one of the world's largest pharmaceutical companies and consistently ranks on the Fortune 500 list of the largest U.S. corporations. For fiscal 2021, it had a total revenue of $46.4 billion.


Ashland is a global, consumer market-focused additives and specialty ingredients company that is responsibly solving for a better world. Through science and a conscious and proactive mindset for sustainability, we serve customers in pharmaceutical, personal care, architectural coatings, construction, energy, food, beverage, and nutraceuticals.


Founded in 1999, Parchem began distributing industrial chemicals and has since established itself as a strategic, reliable, and dominate link in the nutritional, personal care, pharmaceutical, and specialty chemical supply chains. Parchem does not limit itself; we are also experts in providing raw materials to the adhesives and sealants, paints and coatings, agricultural chemicals, excipients, and flavor and fragrance markets. We are headquartered in New Rochelle, NY in the original J.A. Mahlstedt Lumber and Coal building.


SAFC is recognized worldwide as a trusted leader in providing high-quality specialty chemicals and biologics. The SAFC contract manufacturing services business segment offers to pharmaceutical and biopharmaceutical customers GMP custom key intermediates, APIs and drug products with the rare combination of complex small molecule and biologics expertise, providing comprehensive support of product development and manufacturing programs.


BoroPharm Inc. is an environmentally conscious US specialty chemical company serving the pharmaceutical, agrotech, and fine chemical industries. We specialize in offering solutions to your sourcing problems, by manufacturing difficult to source heterocycles, intermediates and registered starting materials. We offer route scouting services, route optimization services, and full contract and custom manufacturing services up to 100 metric ton scale. The value we offer our customers is guaranteeing peace of mind throughout the entire supply chain lifecycle.

Wuhan Fortuna Chemical Co.,Ltd, established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises. It has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement. Since founded, Wuhan Fortuna Chemical Co., Ltd continuously innovates the products and improve the service and sales network. Hence, the company initiates the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Its products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.

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