omeprazole is a proton pump inhibitor used to treat diseases such as peptic ulcer and gastroesophageal reflux disease (GERD), which can specifically act on the site of the proton pump of gastric parietal cells and convert it into the active form of sulfinamide, and then irreversibly bind to the sulfhydryl group of the proton pump through disulfide bonds to generate a complex of sulfinamide and proton pump (H+-K+-ATPase), thereby inhibiting the enzyme activity so that H+ in parietal cells cannot be transported to the gastric cavity, The final step of blocking gastric acid secretion can greatly reduce the amount of gastric acid in gastric juice.
Omeprazole is a proton pump inhibitor that has a strong and prolonged inhibitory effect on gastric acid secretion in animals and humans. It is mainly used for the treatment of peptic ulcer, reflux esophagitis, Zollinger-Ellison syndrome, eradication of Helicobacter pylori.
|Appearance||White or almost white powder||Complies|
|Loss on drying||≤0.5%||0.20%|
|Residue on ignition||≤0.1%||0.07%|
|Residual solvents||Methylene chloride ≤100ppm||76ppm|
Omeprazole CAS 73590-58-6 is a kind of can be used in the treatment of gastroesophageal reflux disease(GERD), gastric and duodenal ulcer and Zollinger-Ellison syndrome oral drugs.It is also used for prophylactic treatment in people at high risk of gastrointestinal bleeding.
Omeprazole stops the stomach from making acid. This causes less heartburn.
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