Dexamethasone 21-phosphate disodium salt is an adrenocortical hormone drug with anti-inflammatory, anti-toxic and anti-allergic effects.
Dexamethasone 21-phosphate disodium salt belongs to the class of adrenocortical hormones, which can stabilize lysosomal membranes, reduce the release of lysosomal hydrolases, inhibit the production of inflammatory substances bradykinin, serotonin and prostaglandins, increase the stability of mast cell granules, and reduce the release of histamine; It constricts blood vessels, inhibits the migration of white blood cells and macrophages outside blood vessels, etc., thus having an anti-inflammatory effect. Dexamethasone 21-phosphate disodium salt can exert immunosuppressive effects by inhibiting macrophage function. Dexamethasone 21-phosphate disodium salt can inhibit fibroblast formation, help prevent corneal scarring, reduce scarring and protect vision when used in trauma. It can inhibit or reduce the formation of new blood vessels in corneal and conjunctival diseases. It is used topically during corneal transplant surgery and surgery to treat myopia to reduce rejection and scarring.
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