Dabigatran etexilate is widely used for venous thromboembolism, secondary prevention of stroke, nonvalvular atrial fibrillation, thromboembolism after elective hip or knee artery replacement in adults, and acute coronary syndrome.
After oral gastrointestinal absorption, dabigatran etexilate is converted to dabigatran with direct anticoagulant activity in vivo, which prevents fibrinogen cleavage to fibrin by binding to the fibrin-specific binding site of thrombin, thereby blocking the final step of the coagulation waterfall network and thrombosis.
|Appearance||White powder||White powder|
|Loss on drying||≤0.5%||0.3%|
|Package details:||1kg/foil bag|
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