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Rifaximin is effective in treating a variety of gastrointestinal diseases such as bacterial intestinal infections, hepatic encephalopathy and inflammatory bowel disease.
Rifaximin has a wide antibacterial spectrum, strong antibacterial effect, can form a high blood concentration in the intestine, and has high antibacterial activity against Staphylococcus aureus, Streptococcus faecalius in gram-positive aerobic bacteria, Salmonella spp., Shigella and Escherichia coli in gram-negative aerobic bacteria, Yersinia enterocolitis, and Bacteroides in gram-positive anaerobic bacteria. Rifaximin works by inhibiting bacterial polymerases, blocking the transcription process of RNA, thereby inhibiting the synthesis of bacterial proteins, thereby reducing ammonia production. The antibacterial effect characteristics of rifaximin: 1) strong antibacterial power, wide antibacterial spectrum, bactericidal effect on most gram-positive bacteria and gram-negative bacteria (including aerobic bacteria and anaerobic bacteria), and the effect on gram-positive bacteria is stronger than that of gram-negative bacteria; 2) It is not absorbed by the gastrointestinal tract, the concentration in the intestine is extremely high, and it quickly exerts an antibacterial effect locally by killing the pathogens of the intestine, and does not need to be combined with intestinal antispasmodics and adsorbents.
Items | Standard | Results |
Appearance | Orange red or deep red crystalline powder | Conforms |
pH value | 4.5~7.5 | 5.5 |
Loss on drying | ≤4.5% | 2.1% |
Residue on ignition | ≤0.1% | Conforms |
Heavy metals | ≤20ppm | Conforms |
Assay | ≥95.0% | 99.1% |
Product parameters | |
Cas number: | 80621-81-4 |
Appearance: | Orange red or deep red crystalline powder |
Purity: | 95%min |
Package details: | 1kg/foil bag; 25kg/drum |
Brand: | Fortunachem |
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