Prazosin hydrochloride is mainly used in the treatment of mild or moderate hypertension, which lowers blood pressure by reducing total peripheral vascular resistance.
Prazosin hydrochloride can relax vascular smooth muscle, expand peripheral blood vessels, reduce peripheral vascular resistance, lower blood pressure, have no effect on presynaptic membrane α2 receptors, but can block the postsynaptic membrane α1, against norepinephrine, neoforin and epinephrine pressor reaction. The biggest advantage of prazosin hydrochloride is that there is no obvious adverse effect on metabolism, has a good effect on blood lipid metabolism, and is especially effective in hypertensive patients with diabetes mellitus or renal insufficiency.
|Appearance||A white or almost white powder||Conform|
|Residue on ignition||≤0.4%||0.01%|
|Water||≤2.0 %||0.2 %|
|Assay||97.0% - 103.0%||99.9%|
|Appearance:||A white or almost white powder|
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